BANDUNG, itb.ac.id- Saturday (12/4) at the Annex Seminar Room, level 3, ITB Rector Complex, Nuning Nuraini, PhD student from Mathematic study program presented her dissertation to attain the doctorate title. The dissertation was titled “Internal and External Mathematics Model of the Spreading of Dengue,” a useful model to show the Dengue endemic in a region. Dengue fever, also known as Bleeding Fever is an epidemic and endemic disease that has yet to have a cure. The disease is caused by the Dengue virus spread by Aedes aegypti, a mosquito that seems to appear everywhere in Indonesia. In solving the problem of spreading, there have been two methods. One of them is by vaccination. Mathematical modeling is important for the analysis of the effect of the vaccine in a population after a test run. Nuraini’s dissertation was exclusive to the study of DBD disease with observing vaccine effect and several vaccination scenarios. Generally the model made by Nuraini shows that there is an endemic in a district for certain parameter values. This can be seen by calculation of the external model equivalence point. The internal model can show if there is a virus appearance in the body whether the immune system is assumed fully functional or not fully functional by looking at the endemic point. This also depends of the parameter values of the chosen internal model. From the internal model study, prediction of length of time the virus remains in the body is related to the average parameter values of infection time which is then used for the external model. The student was born in Malang, 14th April 1974 and is one of the teaching staffs of ITB Mathematics Study Program. Nuraini finished the degree in Mathematics in 1998 and then her masters in 2001. Original article by kristiono